Abstract
Objective: To determine the clinical and epidemiologic aspects of children hospitalized for COVID-19 in a public hospital located in a state in the Brazilian Amazon. Methods: Observational, descriptive, retrospective and documentary study with a quantitative approach to pediatric hospitalization cases due to COVID-19. Results: In the Hospital for Children and Adolescents, a total of 5016 suspected cases of COVID-19 in children were recorded. Of these, 666 were confirmed with the disease and resulted in 140 hospitalizations. We analyzed 136 reports of children hospitalized for COVID-19. Most patients were infants (39%) and preschool children (36%), with a prevalence of males (67.6%) and black/brown race/color (86%). In addition, 83.1% live in urban areas. Regarding the outcome, 96.67% were cured and 3.33% resulted in death. Conclusion: In the Amazonian context, the analysis of the clinical and epidemiologic characteristics of this age group is essential to guide clinical care, predict the severity of the disease and determine the prognosis.
References
Velavan TP, Meyer CG. The COVID-19 epidemic. Trop Med Int Health. 2020 Mar;25(3):278-280. https://doi.10.1111/tmi.13383
Lana RM, Coelho FC, Gomes MFC, Cruz OG, Bastos LS, Villela DAM, et al. Emergência do novo coronavírus (SARS-CoV-2) e o papel de uma vigilância nacional em saúde oportuna e efetiva. Cad Saúde Pública. 2020;36(3). https://doi.org/10.1590/0102-311X00019620
Oliveira WK, Duarte E, França GVA, Garcia LP. Como o Brasil pode deter a COVID-19. Epidemiol Serv Saúde. 2020;29(2). https://doi.org/10.5123/S1679-49742020000200023
Brito SB, Braga IO, Cunha CC, Palácio MAV, Takenami I. Pandemia da COVID-19: o maior desafio do século XXI. Vigil Sanit Debate. 2020;8(2):54-63. https://doi.org/10.22239/2317-269X.01531
Nunes MDR, Pacheco STA, Costa CIA, Silva JA, Xavier WS, Victória JZ. Diagnostic tests and clinical characteristics of covid-19 in children: an integrative review. Texto contexto - enferm. 2020;29. https://doi.org/10.1590/1980-265X-TCE-2020-0156
Superintendência de Vigilância em Saúde-AP. Estado e Fiocruz passam a investigar síndrome pediátrica associada à COVID-19 no Amapá [internet]. Amapá: SVS; 2021 [cited 2021 mar 10]. Available from: https://amapa.gov.br/noticia/1003/estado-e-fiocruz-passam-a-investigar-sindrome-pediatrica-associada-a-covid-19-no-amapa
Nehab MF (Org.). COVID-19 e Saúde da Criança e do Adolescente [internet]. Rio de Janeiro: Fiocruz; 2020 [cited 2023 jan 10]. Available from: https://www.iff.fiocruz.br/pdf/covid19_saude_crianca_adolescente.pdf.
Ministério da Saúde. Doença pelo Novo Coronavírus-COVID-19 Boletim Epidemiológico Especial Semana Epidemiológica 1 2/1 a 8/1/2022 [internet]. Brasil: Ministério da Saúde; 2022 [cited 2022 jan 14]. Available from: https://www.gov.br/saude/pt-br/centrais-de-conteudo/publicacoes/boletins/epidemiologicos/covid-19/2022/boletim-epidemiologico-no-95-boletim-coe-coronavirus.pdf
Superintendência de Vigilância em Saúde-AP. Boletim Epidemiológico Nº 08 Doença pelo coronavírus COVID-19 [internet]. Amapá: SVS; 2020 [cited 2020 jun 06]. Available from: https://editor.amapa.gov.br/arquivos_portais/publicacoes/SVS_a4d7b81791335eb8fa757a148fbaea39.pdf
Butantan. Covid-19 já matou mais de 1.400 crianças de zero a 11 anos no Brasil e deixou outros milhares com sequelas [internet]. São Paulo: Butantan; 2020 [cited 2023 jan 10]. Available from: https://butantan.gov.br/noticias/covid-19-ja-matou-mais-de-1.400-criancas-de-zero-a-11-anos-no-brasil-e-deixou-outras-milhares-com-sequelas?lang=EN
CNN Brasil. Internações por COVID-19 de jovens de até 19 anos em 2021 já superam todo o ano passado, Clipping de notícias detecção digital nº15/2021 [internet]. Brasil: CNN Brasil; 2021 [cited 2021 sept 09]. Available from: https://www.cnnbrasil.com.br/saude/internacoes-por-covid-de-jovens-de-ate-19-anos-em-2021-ja-superam-todo-o-ano-passado/
Superintendência de Vigilância em Saúde-SVS/AP. Painel coronavírus [internet]. Amapá: SVS; 2023 [cited 2020 jun 06]. Available from: http://painel.corona.ap.gov.br/casos/
Governo do Estado do Amapá-Núcleo Hospitalar de Epidemiologia-NHE/HCA. Análise epidemiológica de síndrome gripal (SG), SRAG e casos confirmado de COVID-19 em crianças no Hospital da Criança e do Adolescente (HCA) em 08 abril 2023 [internet]. Amapá: NHE/HCA; 2023 [cited 2023 may 08]. Available from: https://www.portal.ap.gov.br/noticia/0103/boletim-informativo-covid-19-amapa-1-ordm-de-marco-de-2023
Eitan DJ, Berezin N. Vacinação contra a covid-19 em crianças e adolescentes: após a aprovaçao de duas vacinas para a faixa etária pediátrica, há motivos para hesitação? [Internet]. São Paulo : Sociedade de pediatria de São Paulo ; 2022 [cited 2023 Jan 10]. Available from: https://static.poder360.com.br/2022/01/Boletim-Epidemiolo%CC%81gico-96-Coronavi%CC%81rus-24jan2022.pdf.
Hillesheim D, Tomasi YT, Figueiro TH, Paiva KM. Síndrome respiratória aguda grave por COVID-19 em crianças e adolescentes no Brasil: perfil dos óbitos e letalidade hospitalar até a 38a Semana Epidemiológica de 2020. Epidemiol Serv Saude. 2020;29(5):e2020644. https://doi.org/10.1590/S1679-49742020000500021
Safadi MAP, Silva CAA. The challenging and unpredictable spectrum of covid-19 in children and adolescents. Rev paul pediatr. 2021;39. https://doi.org/10.1590/1984-0462/2020/38/2020192
Meena J, Yadav J, Saini L, Yadav A, Kumar J. Clinical Features and Outcome of SARS-CoV-2 Infection in Children: A Systematic Review and Meta-analysis. Indian Pediatr. 2020 Sep 15;57(9):820-826. https://doi.org/10.1007/s13312-020-1961-0
Gruber CN, Patel RS, Trachtman R, Lepow L, Amanat F, Krammer F, et al. Mapping Systemic Inflammation and Antibody Responses in Multisystem Inflammatory Syndrome in Children (MIS-C). Cell. 2020 Nov 12;183(4):982-995.e14. https://doi.org/10.1016/j.cell.2020.09.034
Faria RM, Jantsch LB, Neves ET, Hausen CF, Barros APZ, Sehnem GD, et al. Desigualdades sociais e territoriais na mortalidade de crianças e adolescentes por COVID-19 no Brasil. Rev Bras Enferm. 2022;75(6). https://doi.org/10.1590/0034-7167-2021-0482pt
Zare-Zardini H, Soltaninejad H, Ferdosian F, Hamidieh AA, Memarpoor-Yazdi M. Coronavirus Disease 2019 (COVID-19) in Children: Prevalence, Diagnosis, Clinical Symptoms, and Treatment. Int J Gen Med. 2020 Jul 28;13:477-482. https://doi.org/10.2147/IJGM.S262098
Karimi A ,Tabatabaei S, Rajabnejad M, Pourmoghaddas Z, Rahimi H, Armin S, et al. An Algorithmic Approach to Diagnosis and Treatment of Coronavirus Disease 2019 (COVID-19) in Children: Iranian Expert’s Consensus Statement. Arch Pediatr Infect Dis. 2020;8(2):e102400. https://doi.org/10.5812/pedinfect.102400
Oliveira EA, Colosimo EA, Silva AC, Mak RH, Martelli DB, Silva LR, et al. Clinical characteristics and risk factors for death among hospitalised children and adolescents with COVID-19 in Brazil: an analysis of a nationwide database. Lancet Child Adolesc Health. 2021 Aug 1;5(8):559–68. https://doi.org/10.1016/S2352-4642(21)00134-6
Sankar J, Dhochak N, Kabra SK, Lodha R. COVID-19 in Children: Clinical Approach and Management. Indian J Pediatr. 2020 Jun;87(6):433-442. https://doi:10.1007/s12098-020-03292-1.
Santos RG, Cardoso ELS, Marques LS, França LLA, Xavier TGM, Leon PAP, et al. Perfil clínico-epidemiológico de crianças hospitalizadas: um recorte do período pandêmico e não pandêmico. Esc Anna Nery. 2021;25. https://doi.org/10.1590/2177-9465-EAN-2021-0125
Ministério da Saúde. COVID-19 Painel de Controle [internet]. Brasília: Ministério da Saúde, 2022 [cited 2023 Jan 09]. Available from: https://covid.saude.gov.br/
Molla G, Uzun Ö, Koç N, Yeşil B, Bayhan Gİ. Evaluation of nutritional status in pediatric patients diagnosed with Covid-19 infection. Clin Nutr ESPEN. 2021 Aug;44:424-428. https://doi.org/10.1016/j.clnesp.2021.04.022
Gaythorpe KAM, Bhatia S, Mangal T, Unwin HJT, Imai N, Cuomo-Dannenburg G et al. Children's role in the COVID-19 pandemic: a systematic review of early surveillance data on susceptibility, severity, and transmissibility. Sci Rep. 2021 Jul 6;11(1):13903. https://doi.org/10.1038/s41598-021-92500-
Bezerra JC, Braga HFGM, Melo FMS, Nascimento AP, Silva FBB, Melo ESJ. Manifestações clínicas apresentadas por crianças infectadas pela COVID-19: revisão integrativa. Rev. Eletr. Enferm. 2021 jul 13;23:65966. https://doi.org/10.5216/ree.v23.65966
Carter C, Osborn M, Agagah G, Aedy H, Notter J. COVID-19 disease: invasive ventilation. Clinics in Integrated Care. 2020 Jul;1:100004. https://doi.org/10.1016/j.intcar.2020.100004.
Zimmermann P, Curtis N. Coronavirus Infections in Children Including COVID-19: An Overview of the Epidemiology, Clinical Features, Diagnosis, Treatment and Prevention Options in Children. Pediatr Infect Dis J. 2020 May ;39(5):355-368. https://doi.org/10.1097/INF.0000000000002660
Dong Y, Mo X, Hu Y. Epidemiological characteristics of 2143 pediatric patients with 2019 coronavirus disease in China. J Emerg Med. 2020 Apr;58(4):712–713. https://doi.org/10.1016/j.jemermed.2020.04.006
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright (c) 2024 Array